ZYX Recombinant Rabbit mAb - diagbio | 戴格生物

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ZYX Recombinant Rabbit mAb

db12225

Product Name : ZYX Recombinant Rabbit mAb

Cat.No.: db12225

Synonyms : ESP-2; HED-2

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse

Host species : Rabbit

Background Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Zyxin
Gene ID 7791
Swiss Prot Q15942
Synonyms ESP-2; HED-2
Reactivity Human, Mouse
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:2000-1:10000
IHC: 1:50
ICC/IF: 1:20-1:100
FC: 1:200-1:1000
IP: 1:20
Calculated MW 61 kDa
Observed MW 78 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of ZYX in C6,Rat Brain lysates using ZYX antibody(1:500 diluted).

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