APE1 Recombinant Rabbit mAb - diagbio | 戴格生物

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APE1 Recombinant Rabbit mAb

db11254

Product Name : APE1 Recombinant Rabbit mAb

Cat.No.: db11254

Synonyms : APE; APX; APE1; APEN; APEX; HAP1; REF1

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human APE1
Gene ID 328
Swiss Prot P27695
Synonyms APE; APX; APE1; APEN; APEX; HAP1; REF1
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:2000-1:10000
Calculated MW 36 kDa
Observed MW 36 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of APE1 in K562,C6,3T3,Hela cell lysates using APE1 antibody(1:1000 diluted).

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