Acetyl-Histone H2A.X (Lys5) Recombinant Rabbit mAb - diagbio

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Acetyl-Histone H2A.X (Lys5) Recombinant Rabbit mAb

db12263

Product Name : Acetyl-Histone H2A.X (Lys5) Recombinant Rabbit mAb

Cat.No.: db12263

Synonyms : H2AX; H2A.X; H2A/X

Application : WB, IHC, ICC/IF

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Immunogen A synthetic acetylpeptide corresponding to residues surrounding Lys5 of human Histone H2A.X
Gene ID 3014
Swiss Prot P16104
Synonyms H2AX; H2A.X; H2A/X
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:2000
IHC: 1:200
ICC/IF: 1:200
Calculated MW 15 kDa
Observed MW 15 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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