Interferon Regulatory Factor 4 Recombinant Rabbit mAb - diagbio

产品中心 Products Center

您当前的位置：

Interferon Regulatory Factor 4 Recombinant Rabbit mAb

db12395

Product Name : Interferon Regulatory Factor 4 Recombinant Rabbit mAb

Cat.No.: db12395

Synonyms : MUM1; LSIRF; SHEP8; NF-EM5

Application : WB, IHC, IP

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
Immunogen A synthetic peptide of human MUM1
Gene ID 3662
Swiss Prot Q15306
Synonyms MUM1; LSIRF; SHEP8; NF-EM5
Reactivity Human
Application WB, IHC, IP
Recommended dilution WB: 1:1000
IHC: 1:50
IP: 1:20
Calculated MW 52 kDa
Observed MW 52 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of MUM1 in Ramos cell lysates using MUM1 antibody(1:1000 diluted).

订购信息