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Phospho-ATR (Thr1989) Recombinant Rabbit mAb
db12423
Datasheet

Product Name : Phospho-ATR (Thr1989) Recombinant Rabbit mAb

Cat.No.: db12423

Synonyms : FRP1; MEC1; SCKL; FCTCS; SCKL1

Application : WB

Reactivity : Human

Host species : Rabbit

  • Background The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
  • Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr1989 of human ATR
  • Gene ID 545
  • Swiss Prot Q13535
  • Synonyms FRP1; MEC1; SCKL; FCTCS; SCKL1
  • Reactivity Human
  • Application WB
  • Recommended dilution WB: 1:1000
  • Calculated MW 301 kDa
  • Observed MW 301 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.