ALAD Recombinant Rabbit mAb - diagbio | 戴格生物

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ALAD Recombinant Rabbit mAb

db12431

Product Name : ALAD Recombinant Rabbit mAb

Cat.No.: db12431

Synonyms : PBGS; ALADH

Application : WB, IHC

Reactivity : Human

Host species : Rabbit

Background The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Immunogen A synthetic peptide of human ALAD
Gene ID 210
Swiss Prot P13716
Synonyms PBGS; ALADH
Reactivity Human
Application WB, IHC
Recommended dilution WB: 1:1000
IHC: 1:20-1:100
Calculated MW 36 kDa
Observed MW 36 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from Human fetal liver tissue using db12431 at 1:1000.

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