ABCB11/BSEP Recombinant Rabbit mAb - diagbio | 戴格生物

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ABCB11/BSEP Recombinant Rabbit mAb

db12767

Product Name : ABCB11/BSEP Recombinant Rabbit mAb

Cat.No.: db12767

Synonyms : BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2

Application : IHC, ICC/IF, FC

Reactivity : Human

Host species : Rabbit

Background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human ABCB11/BSEP
Gene ID 8647
Swiss Prot O95342
Synonyms BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2
Reactivity Human
Application IHC, ICC/IF, FC
Recommended dilution IHC: 1:50
ICC/IF: 1:100
FC: 1:50
Calculated MW 146 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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