ITCH Recombinant Rabbit mAb - diagbio | 戴格生物

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ITCH Recombinant Rabbit mAb

db13634

Product Name : ITCH Recombinant Rabbit mAb

Cat.No.: db13634

Synonyms : AIF4; AIP4; ADMFD; NAPP1

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
Immunogen A synthetic peptide of human ITCH/AIP4
Gene ID 83737
Swiss Prot Q96J02
Synonyms AIF4; AIP4; ADMFD; NAPP1
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 103 kDa
Observed MW 103 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of ITCH/AIP4 in A549,HL-60 cell lysates using ITCH/AIP4 antibody(1:1000 diluted).

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