Phospho-PKR (Thr446) Recombinant Rabbit mAb - diagbio | 戴格生物

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Phospho-PKR (Thr446) Recombinant Rabbit mAb

db14038

Product Name : Phospho-PKR (Thr446) Recombinant Rabbit mAb

Cat.No.: db14038

Synonyms : PKR; PRKR; EIF2AK1; PPP1R83

Application : WB, IHC, IP, ChIP

Reactivity : Human, Mouse

Host species : Rabbit

Background The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr446 of human PKR
Gene ID 5610
Swiss Prot P19525
Synonyms PKR; PRKR; EIF2AK1; PPP1R83
Reactivity Human, Mouse
Application WB, IHC, IP, ChIP
Recommended dilution WB: 1:1000
IHC: 1:100
IP: 1:20
ChIP: 1:20
Calculated MW 62 kDa
Observed MW 74 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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