IL23 Recombinant Rabbit mAb - diagbio | 戴格生物

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IL23 Recombinant Rabbit mAb

db14843

Product Name : IL23 Recombinant Rabbit mAb

Cat.No.: db14843

Synonyms : CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B

Application : WB

Reactivity : Human

Host species : Rabbit

Background This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human IL23
Gene ID 3593
Swiss Prot P29460
Synonyms CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B
Reactivity Human
Application WB
Recommended dilution WB: 1:1000
Calculated MW 21 kDa
Observed MW 21 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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