Phospho-Cytokeratin 8 (Ser23) Recombinant Rabbit mAb - diagbio

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Phospho-Cytokeratin 8 (Ser23) Recombinant Rabbit mAb

db14947

Product Name : Phospho-Cytokeratin 8 (Ser23) Recombinant Rabbit mAb

Cat.No.: db14947

Synonyms : K8; KO; CK8; CK-8; CYK8; K2C8; CARD2

Application : WB, IHC, ICC/IF, IP

Reactivity : Human

Host species : Rabbit

Background This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser23 of human Cytokeratin 8
Gene ID 3856
Swiss Prot P05787
Synonyms K8; KO; CK8; CK-8; CYK8; K2C8; CARD2
Reactivity Human
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:2000-1:10000
IHC: 1:20
ICC/IF: 1:20
IP: 1:20
Calculated MW 54 kDa
Observed MW 54 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Phospho-Cytokeratin 8 (Ser23) in K562,Hela cell lysates using Phospho-Cytokeratin 8 (Ser23) antibody(1:1000 diluted).

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