Integrin beta 4 Recombinant Rabbit mAb - diagbio | 戴格生物

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Integrin beta 4 Recombinant Rabbit mAb

db15170

Product Name : Integrin beta 4 Recombinant Rabbit mAb

Cat.No.: db15170

Synonyms : CD104; GP150

Application : WB, ICC/IF

Reactivity : Human

Host species : Rabbit

Background Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Integrin beta 4
Gene ID 3691
Swiss Prot P16144
Synonyms CD104; GP150
Reactivity Human
Application WB, ICC/IF
Recommended dilution WB: 1:1000-1:5000
ICC/IF: 1:50-1:200
Calculated MW 202 kDa
Observed MW 202 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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