Integrin alpha 6 Recombinant Rabbit mAb - diagbio | 戴格生物

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Integrin alpha 6 Recombinant Rabbit mAb

db15455

Product Name : Integrin alpha 6 Recombinant Rabbit mAb

Cat.No.: db15455

Synonyms : CD49f; VLA-6; ITGA6B

Application : WB, IHC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Immunogen A synthetic peptide of human Integrin alpha 6
Gene ID 3655
Swiss Prot P23229
Synonyms CD49f; VLA-6; ITGA6B
Reactivity Human, Mouse, Rat
Application WB, IHC
Recommended dilution WB: 1:1000
IHC: 1:20-1:500
Calculated MW 127 kDa
Observed MW 127 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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