Interferon regulatory factor 9 Recombinant Rabbit mAb - diagbio

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Interferon regulatory factor 9 Recombinant Rabbit mAb

db15521

Product Name : Interferon regulatory factor 9 Recombinant Rabbit mAb

Cat.No.: db15521

Synonyms : p48; IRF-9; ISGF3; ISGF3G

Application : WB, ICC/IF, FC

Reactivity : Human

Host species : Rabbit

Background Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Immunogen A synthetic peptide of human Interferon regulatory factor 9
Gene ID 10379
Swiss Prot Q00978
Synonyms p48; IRF-9; ISGF3; ISGF3G
Reactivity Human
Application WB, ICC/IF, FC
Recommended dilution WB: 1:2000-1:10000
ICC/IF: 1:20-1:50
FC: 1:20
Calculated MW 44 kDa
Observed MW 44 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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