ABCD1 Rabbit pAb - diagbio | 戴格生物

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ABCD1 Rabbit pAb

db1581

Product Name : ABCD1 Rabbit pAb

Cat.No.: db1581

Synonyms : ALD; AMN; ALDP; ABC42

Application : WB, ICC/IF, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human ABCD1
Gene ID 215
Swiss Prot P33897
Synonyms ALD; AMN; ALDP; ABC42
Reactivity Human, Mouse, Rat
Application WB, ICC/IF, FC
Recommended dilution WB: 1:2000
ICC/IF: 1:20
FC: 1:20
Calculated MW 83 kDa
Observed MW 83 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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