Phospho-PRC1 (Thr481) Rabbit pAb - diagbio | 戴格生物

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Phospho-PRC1 (Thr481) Rabbit pAb

db1687

Product Name : Phospho-PRC1 (Thr481) Rabbit pAb

Cat.No.: db1687

Synonyms : ASE1

Application : WB, IHC, ICC/IF

Reactivity : Human

Host species : Rabbit

Background This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr481 of human PRC1
Gene ID 9055
Swiss Prot O43663
Synonyms ASE1
Reactivity Human
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
Calculated MW 72 kDa
Observed MW 72 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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