Phospho-PLCG 2 (Tyr759) Rabbit pAb - diagbio | 戴格生物

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Phospho-PLCG 2 (Tyr759) Rabbit pAb

db20266

Product Name : Phospho-PLCG 2 (Tyr759) Rabbit pAb

Cat.No.: db20266

Synonyms : FCAS3; APLAID; PLC-IV; PLC-gamma-2

Application : WB, ICC/IF, IP

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr759 of human PLCG 2
Gene ID 5336
Swiss Prot P16885
Synonyms FCAS3; APLAID; PLC-IV; PLC-gamma-2
Reactivity Human
Application WB, ICC/IF, IP
Recommended dilution WB: 1:2000-1:10000
ICC/IF: 1:20
IP: 1:20
Calculated MW 148 kDa
Observed MW 148 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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