Phospho-BRAF (Ser729) Rabbit pAb
Product Name :
Phospho-BRAF (Ser729) Rabbit pAb
Cat.No.:
db20383
Synonyms :
NS7; B-raf; BRAF1; RAFB1; B-RAF1
Application :
WB, IHC
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser729 of human BRAF
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Gene ID
673
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Swiss Prot
P15056
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Synonyms
NS7; B-raf; BRAF1; RAFB1; B-RAF1
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC
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Recommended dilution
WB: 1:1000
IHC: 1:50
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Calculated MW
84 kDa
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Observed MW
84 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.