Phospho-beta Arrestin 1 (Ser412) Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

Phospho-beta Arrestin 1 (Ser412) Rabbit pAb

db20801

Product Name : Phospho-beta Arrestin 1 (Ser412) Rabbit pAb

Cat.No.: db20801

Synonyms : ARB1; ARR1

Application : WB, IHC, ICC/IF, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser412 of human beta Arrestin 1
Gene ID 408
Swiss Prot P49407
Synonyms ARB1; ARR1
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:5000
IHC: 1:100
ICC/IF: 1:50
IP: 1:20
Calculated MW 50 kDa
Observed MW 50 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息