Acetyl Coenzyme A carboxylase alpha Rabbit pAb - diagbio | 戴格生物

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Acetyl Coenzyme A carboxylase alpha Rabbit pAb

db22513

Product Name : Acetyl Coenzyme A carboxylase alpha Rabbit pAb

Cat.No.: db22513

Synonyms : ACC; ACAC; ACC1; ACCA; ACACAD

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human Acetyl Coenzyme A carboxylase alpha
Gene ID 31
107476
60581
Swiss Prot O00763
Q5SWU9
P11497
Synonyms ACC; ACAC; ACC1; ACCA; ACACAD
Reactivity Human,Mouse,Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:200
ICC/IF: 1:50
FC: 1:200
IP: 1:20
Calculated MW 277 kDa
Observed MW 277 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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