Phospho-PLCG2 (Tyr1217) Rabbit pAb
Product Name :
Phospho-PLCG2 (Tyr1217) Rabbit pAb
Cat.No.:
db24437
Synonyms :
FCAS3; APLAID; PLC-IV; PLC-gamma-2
Application :
WB
Reactivity :
Human
Host species :
Rabbit
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Background
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr1217 of human PLCG2
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Gene ID
5336
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Swiss Prot
P16885
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Synonyms
FCAS3; APLAID; PLC-IV; PLC-gamma-2
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
148 kDa
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Observed MW
150 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.