Phospho-Cdk1/Cdk2/Cdk3 (Thr14) Rabbit pAb - diagbio | 戴格生物

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Phospho-Cdk1/Cdk2/Cdk3 (Thr14) Rabbit pAb

db2492

Product Name : Phospho-Cdk1/Cdk2/Cdk3 (Thr14) Rabbit pAb

Cat.No.: db2492

Synonyms : CDC2; CDC28A; P34CDC2

Application : WB, IHC, ICC/IF, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr14 of human Cdk1
Gene ID 983
Swiss Prot P06493
Synonyms CDC2; CDC28A; P34CDC2
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
IP: 1:20
Calculated MW 34 kDa
Observed MW 34 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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