Phospho-PKC epsilon (Ser729) Rabbit pAb
Product Name :
Phospho-PKC epsilon (Ser729) Rabbit pAb
Cat.No.:
db2814
Synonyms :
PKCE; nPKC-epsilon
Application :
WB
Reactivity :
Human, Rat
Host species :
Rabbit
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Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Ser729 of human PKC epsilon
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Gene ID
5581
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Swiss Prot
Q02156
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Synonyms
PKCE; nPKC-epsilon
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Reactivity
Human, Rat
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
84 kDa
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Observed MW
84 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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