Phospho-BubR1 (Thr680) Rabbit pAb - diagbio | 戴格生物

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Phospho-BubR1 (Thr680) Rabbit pAb

db3486

Product Name : Phospho-BubR1 (Thr680) Rabbit pAb

Cat.No.: db3486

Synonyms : MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta

Application : WB, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr680 of human BubR1
Gene ID 701
Swiss Prot O60566
Synonyms MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta
Reactivity Human
Application WB, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:20
FC: 1:50
IP: 1:20
Calculated MW 120 kDa
Observed MW 120 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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