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Phospho-c-Myc (Ser62) Rabbit pAb

Product Name : Phospho-c-Myc (Ser62) Rabbit pAb

Cat.No.: db4573

Synonyms : MRTL; MYCC; c-Myc; bHLHe39

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
  • Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser62 of human c-Myc
  • Gene ID 4609
  • Swiss Prot P01106
  • Synonyms MRTL; MYCC; c-Myc; bHLHe39
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000
    IHC: 1:200
    ICC/IF: 1:200
    FC: 1:20
    IP: 1:20
  • Calculated MW 49 kDa
  • Observed MW 57 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.