Phospho-ATR (Thr1989) Rabbit pAb
Product Name :
Phospho-ATR (Thr1989) Rabbit pAb
Cat.No.:
db4816
Synonyms :
FRP1; MEC1; SCKL; FCTCS; SCKL1
Application :
WB
Reactivity :
Human
Host species :
Rabbit
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Background
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Thr1989 of human ATR
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Gene ID
545
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Swiss Prot
Q13535
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Synonyms
FRP1; MEC1; SCKL; FCTCS; SCKL1
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
301 kDa
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Observed MW
301 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.