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Recombinant Mouse CSF1R / MCSF Receptor / CD115 Protein (His & Fc tag)
db57998
Datasheet
- Background Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. Activates several signaling pathways in response to ligand binding, including the ERK1/2 and the JNK pathway
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Gene ID
12978
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Swiss Prot
P09581
- Synonyms AI323359;CD115;CSF-1R;Csfmr;Fim-2;Fms;M-CSF-R;M-CSFR
- Application Positive Control, Immunogen, SDS-PAGE, WB
- Molecular Weight 83.3 kDa
- Species Mouse
- Expression Host HEK293 Cells
- Purity >95% as determined by SDS-PAGE.
- Seq Met1-Ser511
- Tag C-His-Fc
- Formulation Freeze-dried powder
- Storage/Stability Aliquot and store at -20℃ to -80℃ for up to 6 months. Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose; buffer containing 50% glycerol is recommen.
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15% SDS PAGE(reduced) analysis of Recombinant Mouse CSF1R / MCSF Receptor / CD115 Protein (His & Fc tag)
订购信息
- Package Price (RMB)
- 10μg 860
- 50μg 1560
- 100μg 2560
- 1mg 14600
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
