Phospho-PDGF Receptor alpha (Tyr720) Rabbit pAb - diagbio | 戴格生物

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Phospho-PDGF Receptor alpha (Tyr720) Rabbit pAb

db8020

Product Name : Phospho-PDGF Receptor alpha (Tyr720) Rabbit pAb

Cat.No.: db8020

Synonyms : CD140A; PDGFR2; PDGFR-2

Application : WB, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr720 of human PDGFR alpha
Gene ID 5156
Swiss Prot P16234
Synonyms CD140A; PDGFR2; PDGFR-2
Reactivity Human, Mouse, Rat
Application WB, FC
Recommended dilution WB: 1:1000
FC: 1:100-1:500
Calculated MW 123 kDa
Observed MW 190 kDa
Host species Rabbit
Clonality Polyclonal
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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