STAT3 Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

STAT3 Rabbit pAb

db1086

Datasheet

Product Name : STAT3 Rabbit pAb

Cat.No.: db1086

Synonyms : APRF; HIES; ADMIO; ADMIO1

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]
Immunogen A synthetic peptide of human STAT3
Gene ID 6774
Swiss Prot P40763
Synonyms APRF; HIES; ADMIO; ADMIO1
Reactivity Human
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:50
FC: 1:20
IP: 1:20
Calculated MW 88 kDa
Observed MW 88 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息

Package Price (RMB)
20μL 598
50μL 998
100μL 1798
货期：现货