BackgroundPredicted to enable CCR5 chemokine receptor binding activity. Acts upstream of or within cell projection morphogenesis; negative regulation of neuron apoptotic process; and nervous system development. Located in cytoplasm and intermediate filament. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; foregut-midgut junction; and metanephros. Orthologous to human NES (nestin). [provided by Alliance of Genome Resources, Apr 2022]
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Western blot analysis of extracts from Neuro-2a cells using db11140 at 1:1000.