ABCG2 Recombinant Rabbit mAb - diagbio | 戴格生物

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ABCG2 Recombinant Rabbit mAb

db11489

Product Name : ABCG2 Recombinant Rabbit mAb

Cat.No.: db11489

Synonyms : MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; MXR-1; CDw338; UAQTL1; EST157481

Application : WB

Reactivity : Human

Host species : Rabbit

Background The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Immunogen A synthetic peptide of human BCRP/ABCG2
Gene ID 9429
Swiss Prot Q9UNQ0
Synonyms MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; MXR-1; CDw338; UAQTL1; EST157481
Reactivity Human
Application WB
Recommended dilution WB: 1:1000
Calculated MW 72 kDa
Observed MW 72 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of BCRP/ABCG2 in HepG2,U251,HL-60 using BCRP/ABCG2 antibody(1:1000 diluted)

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