ABCG2 Recombinant Rabbit mAb
Product Name :
ABCG2 Recombinant Rabbit mAb
Cat.No.:
db11489
Synonyms :
MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; MXR-1; CDw338; UAQTL1; EST157481
Application :
WB
Reactivity :
Human
Host species :
Rabbit
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Background
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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Immunogen
A synthetic peptide of human BCRP/ABCG2
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Gene ID
9429
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Swiss Prot
Q9UNQ0
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Synonyms
MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; MXR-1; CDw338; UAQTL1; EST157481
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
72 kDa
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Observed MW
72 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of BCRP/ABCG2 in HepG2,U251,HL-60 using BCRP/ABCG2 antibody(1:1000 diluted)
订购信息
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Package
Price (RMB)
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20μL
850
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50μL
1400
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100μL
2400
- 货期:现货
For research use only. Not intended for diagnostic.