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YB1 (DGR20520) Rabbit mAb
db11545
Datasheet
- Background This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]
- Immunogen A synthetic peptide of human YB1
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Gene ID
4904
-
Swiss Prot
P67809
- Synonyms YB1; BP-8; CSDB; DBPB; YB-1; CBF-A; CSDA2; EFI-A; NSEP1; NSEP-1; MDR-NF1
- Reactivity Human,Mouse
- Application WB, IHC-P, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000
IHC-P: 1:500-1:2000
ICC/IF: 1:100
FC: 1:200-1:500
IP: 1:20-1:50 - Calculated MW 36 kDa
- Observed MW 49 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR20520
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of YB1 in Hela,C2C12 cell lysates using YB1 antibody(1:1000 diluted). -
Western blot analysis of extracts from HeLa cells using db11545 at 1:1000. -
Immunohistochemical analysis of paraffin-embedded human colon cancer using db11545 antibody. -
Immunofluorescent analysis of HeLa cells using db11545 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
