Zonula occludens protein 3 Recombinant Rabbit mAb - diagbio

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Zonula occludens protein 3 Recombinant Rabbit mAb

db12068

Product Name : Zonula occludens protein 3 Recombinant Rabbit mAb

Cat.No.: db12068

Synonyms : ZO3; ZO-3

Application : WB

Reactivity : Human, Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012]
Immunogen A synthetic peptide of human Zonula occludens protein 3
Gene ID 27134
Swiss Prot O95049
Synonyms ZO3; ZO-3
Reactivity Human, Rat
Application WB
Recommended dilution WB: 1:2000-1:10000
Calculated MW 101 kDa
Observed MW 140 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Zonula occludens protein 3 in MCF-7，Caco2 cell lysates using Zonula occludens protein 3 antibody(1:1000 diluted).

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