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Amyloid Precursor Protein Recombinant Rabbit mAb
db12240
Datasheet

Product Name : Amyloid Precursor Protein Recombinant Rabbit mAb

Cat.No.: db12240

Synonyms : AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; preA4; CTFgamma

Application : WB, IP

Reactivity : Human

Host species : Rabbit

  • Background This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
  • Immunogen A synthetic peptide of human Amyloid Precursor Protein
  • Gene ID 351
  • Swiss Prot P05067
  • Synonyms AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; preA4; CTFgamma
  • Reactivity Human
  • Application WB, IP
  • Recommended dilution WB: 1:1000
    IP: 1:20
  • Calculated MW 87 kDa
  • Observed MW 100 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of Amyloid Precursor Protein in Hela cell lysates using Amyloid Precursor Protein antibody(1:500 diluted).
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.