ZAP70 Recombinant Rabbit mAb - diagbio | 戴格生物

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ZAP70 Recombinant Rabbit mAb

db12267

Product Name : ZAP70 Recombinant Rabbit mAb

Cat.No.: db12267

Synonyms : SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70

Application : WB, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human ZAP70
Gene ID 7535
Swiss Prot P43403
Synonyms SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70
Reactivity Human, Mouse, Rat
Application WB, FC, IP
Recommended dilution WB: 1:1000
FC: 1:20
IP: 1:20
Calculated MW 70 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of ZAP70 in Jurkat cell lysates using ZAP70 antibody(1:1000 diluted).

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