产品中心 Products Center
ABAT Recombinant Rabbit mAb
db12293
Datasheet

Product Name : ABAT Recombinant Rabbit mAb

Cat.No.: db12293

Synonyms : GABAT; NPD009; GABA-AT

Application : WB, IHC, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic peptide of human ABAT
  • Gene ID 18
  • Swiss Prot P80404
  • Synonyms GABAT; NPD009; GABA-AT
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, FC, IP
  • Recommended dilution WB: 1:2000-1:10000
    IHC: 1:50-1:200
    FC: 1:20
    IP: 1:20-1:50
  • Calculated MW 56 kDa
  • Observed MW 56 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of ABAT/GABA-T in Rat Brain lysates using ABAT/GABA-T antibody(1:1000 diluted).
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.