ABAT Recombinant Rabbit mAb
Product Name :
ABAT Recombinant Rabbit mAb
Cat.No.:
db12293
Synonyms :
GABAT; NPD009; GABA-AT
Application :
WB, IHC, FC, IP
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic peptide of human ABAT
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Gene ID
18
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Swiss Prot
P80404
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Synonyms
GABAT; NPD009; GABA-AT
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC, FC, IP
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Recommended dilution
WB: 1:2000-1:10000
IHC: 1:50-1:200
FC: 1:20
IP: 1:20-1:50
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Calculated MW
56 kDa
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Observed MW
56 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of ABAT/GABA-T in Rat Brain lysates using ABAT/GABA-T antibody(1:1000 diluted).
订购信息
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Package
Price (RMB)
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20μL
850
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50μL
1400
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100μL
2400
- 货期:现货
For research use only. Not intended for diagnostic.