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Activin Receptor Type IIB Recombinant Rabbit mAb
db12436
Datasheet

Product Name : Activin Receptor Type IIB Recombinant Rabbit mAb

Cat.No.: db12436

Synonyms : HTX4; ACTRIIB; ActR-IIB

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic peptide of human Activin Receptor Type IIB/ACVR2B
  • Gene ID 93
  • Swiss Prot Q13705
  • Synonyms HTX4; ACTRIIB; ActR-IIB
  • Reactivity Human, Mouse, Rat
  • Application WB
  • Recommended dilution WB: 1:1000
  • Calculated MW 58 kDa
  • Observed MW 58 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of Activin Receptor Type IIB/ACVR2B in CHO-K1,mouse Brain using Activin Receptor Type IIB/ACVR2B antibody(1:1000 diluted)
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.