Cleaved PARP1 Recombinant Rabbit mAb - diagbio | 戴格生物

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Cleaved PARP1 Recombinant Rabbit mAb

db12579

Product Name : Cleaved PARP1 Recombinant Rabbit mAb

Cat.No.: db12579

Synonyms : PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1

Application : WB, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Cleaved PARP1
Gene ID 142
Swiss Prot P09874
Synonyms PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1
Reactivity Human
Application WB, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:100
FC: 1:20
IP: 1:20
Calculated MW 113 kDa
Observed MW 89 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Cleaved PARP1 in K562 cell lysates using Cleaved PARP1 antibody(1:1000 diluted).

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