Cleaved PARP1 (DGR14663) Rabbit mAb
Product Name :
Cleaved PARP1 (DGR14663) Rabbit mAb
Cat.No.:
db12579
Synonyms :
PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1
Application :
WB, ICC/IF, FC, IP
Reactivity :
Human
Host species :
Rabbit
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Background
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic peptide of human Cleaved PARP1
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Gene ID
142
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Swiss Prot
P09874
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Synonyms
PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1
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Reactivity
Human
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Application
WB, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000
ICC/IF: 1:200-1:500
FC: 1:20-1:50
IP: 1:50
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Calculated MW
113 kDa
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Observed MW
89 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR14663
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Cleaved PARP1 in K562 cell lysates using Cleaved PARP1 antibody(1:1000 diluted).
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Western blot analysis of extracts from Jurkat cells using db12579 at 1:1000.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.