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Phospho-FAK (Tyr576) Recombinant Rabbit mAb
db13741
Datasheet
- Background This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr576 of human FAK
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Gene ID
5747
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Swiss Prot
Q05397
- Synonyms FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
- Reactivity Human, Mouse, Rat
- Application WB, FC
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Recommended dilution
WB: 1:2000-1:10000
FC: 1:20 - Calculated MW 119 kDa
- Observed MW 125 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of FAK (phospho-Tyr576) in A549,U251,C2C12 cell lysates using FAK (phospho-Tyr576) antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
