Phospho-Smad3 (Ser423/Ser425) Recombinant Rabbit mAb - diagbio

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Phospho-Smad3 (Ser423/Ser425) Recombinant Rabbit mAb

db13792

Product Name : Phospho-Smad3 (Ser423/Ser425) Recombinant Rabbit mAb

Cat.No.: db13792

Synonyms : LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Application : WB, IHC, ICC/IF

Reactivity : Human, Mouse

Host species : Rabbit

Background The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser423/Ser425 of human Smad3
Gene ID 4088
Swiss Prot P84022
Synonyms LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436
Reactivity Human, Mouse
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:100-1:200
ICC/IF: 1:100-1:200
Calculated MW 48 kDa
Observed MW 52 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Phospho-Smad3 (Ser423/425) in Jurkat,C6,CHO-K1,Hela cell lysates using Phospho-Smad3 (Ser423/425) antibody(1:1000 diluted).

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