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alpha Actinin 4 Recombinant Rabbit mAb
db13796
Datasheet

Product Name : alpha Actinin 4 Recombinant Rabbit mAb

Cat.No.: db13796

Synonyms : FSGS; FSGS1; ACTININ-4

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic peptide of human alpha Actinin 4
  • Gene ID 81
  • Swiss Prot O43707
  • Synonyms FSGS; FSGS1; ACTININ-4
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000-1:5000
    IHC: 1:20-1:100
    ICC/IF: 1:20-1:50
    FC: 1:20
    IP: 1:20-1:50
  • Calculated MW 105 kDa
  • Observed MW 105 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of alpha Actinin 4 in K562,Rat Brain,C6,3T3,Hela cell lysates using alpha Actinin 4 antibody(1:1000 diluted).
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.