产品中心 Products Center
Phospho-AMPK alpha 2 (Ser491) Recombinant Rabbit mAb
db13946
Datasheet

Product Name : Phospho-AMPK alpha 2 (Ser491) Recombinant Rabbit mAb

Cat.No.: db13946

Synonyms : AMPK; AMPK2; PRKAA; AMPKa2

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser491 of human AMPK alpha 2
  • Gene ID 5563
  • Swiss Prot P54646
  • Synonyms AMPK; AMPK2; PRKAA; AMPKa2
  • Reactivity Human, Mouse, Rat
  • Application WB
  • Recommended dilution WB: 1:1000-1:5000
  • Calculated MW 62 kDa
  • Observed MW 62 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.