BackgroundThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015]
ImmunogenRecombinant protein of human P70 S6 Kinase beta
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Western blot detection of P70 S6 Kinase beta in Rat Brain,C6,Hela cell lysates using P70 S6 Kinase beta antibody(1:1000 diluted).
Western blot analysis of extracts from Jurkat cells using db14017 at 1:5000.
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using db14017 antibody.
Immunofluorescent analysis of 3T3 cells using db14017 antibody (green), and DAPI (blue).