YTHDC2 (DGR16937) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

YTHDC2 (DGR16937) Rabbit mAb

db14046

Datasheet

Product Name : YTHDC2 (DGR16937) Rabbit mAb

Cat.No.: db14046

Synonyms : CAHL; hYTHDC2

Application : WB, IHC-P, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]
Immunogen Recombinant protein of human YTHDC2
Gene ID 64848
Swiss Prot B2RR83
Synonyms CAHL; hYTHDC2
Reactivity Human,Mouse,Rat
Application WB, IHC-P, FC, IP
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:500
FC: 1:200-1:500
IP: 1:20-1:50
Calculated MW 160 kDa
Observed MW 160 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR16937
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of YTHDC2 in Hela,A549,HL-60,U251,U87-MG cell lysates using YTHDC2 antibody(1:1000 diluted).

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