NEDD4 Recombinant Rabbit mAb - diagbio | 戴格生物

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NEDD4 Recombinant Rabbit mAb

db14224

Product Name : NEDD4 Recombinant Rabbit mAb

Cat.No.: db14224

Synonyms : RPF1; NEDD4-1

Application : WB, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]
Immunogen A synthetic peptide of human NEDD4
Gene ID 4734
Swiss Prot P46934
Synonyms RPF1; NEDD4-1
Reactivity Human, Mouse, Rat
Application WB, FC, IP
Recommended dilution WB: 1:2000-1:10000
FC: 1:20
IP: 1:20
Calculated MW 149 kDa
Observed MW 115 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of NEDD4 in Hela,A549,HL-60,U2OS,U87-MG cell lysates using NEDD4 antibody(1:1000 diluted).

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