Phospho-ERK1/2 (Thr202/Thr185) (DGR12177) Rabbit mAb - diagbio

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Recombinant DGRmAb^®

Phospho-ERK1/2 (Thr202/Thr185) (DGR12177) Rabbit mAb

db14364

Datasheet

Product Name : Phospho-ERK1/2 (Thr202/Thr185) (DGR12177) Rabbit mAb

Cat.No.: db14364

Synonyms : ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK

Application : WB, IHC-P, ICC/IF, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr202 of human ERK1
Gene ID 5595
Swiss Prot P27361
Synonyms ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, IP
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:500
ICC/IF: 1:100
IP: 1:20-1:50
Calculated MW 43,41 kDa
Observed MW 44,42 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR12177
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Phospho-p44/42 MAPK (ERK1/2) (Thr202) in C6,Hela cell lysates using Phospho-p44/42 MAPK (ERK1/2) (Thr202) antibody(1:1000 diluted).

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