Acetyl Coenzyme A Carboxylase (DGR20960) Rabbit mAb - diagbio

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Recombinant DGRmAb^®

Acetyl Coenzyme A Carboxylase (DGR20960) Rabbit mAb

db14523

Datasheet

Product Name : Acetyl Coenzyme A Carboxylase (DGR20960) Rabbit mAb

Cat.No.: db14523

Synonyms : ACC; ACAC; ACC1; ACCA; ACACAD

Application : WB, IHC-P, ICC/IF, FC

Reactivity : Human

Host species : Rabbit

Background Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Acetyl Coenzyme A Carboxylase
Gene ID 31
Swiss Prot O00763
Synonyms ACC; ACAC; ACC1; ACCA; ACACAD
Reactivity Human
Application WB, IHC-P, ICC/IF, FC
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:200-1:500
ICC/IF: 1:100-1:200
FC: 1:100-1:500
Calculated MW 277 kDa
Observed MW 277 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR20960
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Acetyl Coenzyme A Carboxylase in Hela,HCT116 cell lysates using Acetyl Coenzyme A Carboxylase antibody(1:1000 diluted).

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