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p18 INK4c (DGR14762) Rabbit mAb
db14538
Datasheet
- Background The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human p18 INK4c
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Gene ID
1031
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Swiss Prot
P42773
- Synonyms p18; INK4C; p18-INK4C
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:50
ICC/IF: 1:100
IP: 1:20-1:50 - Calculated MW 18 kDa
- Observed MW 18 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14762
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of p18 INK4c/CDKN2C in C6 cell lysates using p18 INK4c/CDKN2C antibody(1:500 diluted). -
Immunohistochemical analysis of paraffin-embedded human breast cancer using db14538 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
