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p53 Recombinant Rabbit mAb
db14679
Datasheet

Product Name : p53 Recombinant Rabbit mAb

Cat.No.: db14679

Synonyms : bbl; bfy; bhy; p44; p53; Tp53

Application : WB, ICC/IF, FC, IP

Reactivity : Mouse

Host species : Rabbit

  • Background This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mice deficient for this gene are developmentally normal but are susceptible to spontaneous tumors. Evidence to date shows that this gene contains one promoter, in contrast to alternative promoters of the human gene, and transcribes a few of splice variants which encode different isoforms, although the biological validity or the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
  • Immunogen Recombinant protein of mouse p53
  • Gene ID 22059
  • Swiss Prot P02340
  • Synonyms bbl; bfy; bhy; p44; p53; Tp53
  • Reactivity Mouse
  • Application WB, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000
    ICC/IF: 1:100
    FC: 1:50
    IP: 1:20
  • Calculated MW 44 kDa
  • Observed MW 53 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot detection of p53 in 3T3 cell lysates using p53 antibody(1:1000 diluted).
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.