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Angiotensinogen (DGR16785) Rabbit mAb
db14800
Datasheet
- Background The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of mouse Angiotensinogen
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Gene ID
183
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Swiss Prot
P01019
- Synonyms AGT;ANHU; hFLT1; SERPINA8
- Reactivity Human,Mouse,Rat
- Application WB, IP
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Recommended dilution
WB: 1:1000
IP: 1:20-1:50 - Calculated MW 52 kDa
- Observed MW 52 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR16785
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from PC-12 cells using db14800 at 1:1000. -
Western blot analysis of extracts from HepG2,U2OS,C2C12 cells using db14800 at 1:1000.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
